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From a total of citations identified, 35 studies 5 - 28 , 30 - 40 were included for qualitative synthesis. Although conclusive inferences are difficult, considering the variability in the factors adjusted for in the included studies eTable 1 in the Supplement and the availability of far fewer studies in the adjusted analyses compared with the unadjusted analyses, we hypothesize that the findings of an association of women with increased mortality are significantly confounded by differences in traditional cardiovascular risk factors, sex-specific differences in clinical presentation and response by the medical infrastructure in women compared with men with STEMI. PubMed Google Scholar Crossref. Also, we performed 3 sensitivity analyses: Influence of female sex on long-term mortality after acute coronary syndromes treated by percutaneous coronary intervention: Chin Med J Engl. Trends in treatment and outcomes for acute myocardial infarction:

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However, 3 RCTs 30 , 33 , 39 and 2 RCTs 30 , 33 respectively reported sex-specific 1 year all-cause mortality with unadjusted and adjusted rick estimates, and hence we have reported the meta-analytic estimate for 1-year all-cause mortality for the unadjusted and adjusted analyses. Is there a gender difference in outcome following primary PCI?

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Sex-related differences in outcome after ST-segment elevation myocardial infarction treated by primary angioplasty: Measuring inconsistency in meta-analyses. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. From a total of citations identified, 35 studies 5 - 28 , 30 - 40 were included for qualitative synthesis. Create a free personal account to make a comment, download free article PDFs, sign up for alerts and more. However, when adjusted RRs were used, the association between women and higher risk of all-cause mortality was attenuated but still significantly elevated for in-hospital mortality RR, 1. Inadequate risk adjustment in the included studies may well explain the incomplete attenuation of higher risk for mortality in women in our adjusted analysis.

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